What is the drug card of Cimetidine?

Generic name, Trade name, GI agent, Prototype, Indications/Uses, Route and Dosage, Pharmacodynamics, Pharmacokinetics, Contraindiations, Adverse/ Side Effects, Nursing Implications, Patient鈥檚 education.

Here is a drug Study:

Generic name:Cimetidine
Trade name:Tagamet庐, Tagamet庐 HB, Tagamet庐, Tiltab庐
GI agent: Antacid.
Prototype:H2-antagonists

Indications/Uses:
Duodenal ulcers, active gastric ulcers, gastroesophageal reflux disease (GERD), pathological hypersecretory conditions (e.g., Zollinger Ellison syndrome), heartburn and the prevention of gastrointestinal bleeding.
Used sometimes to treat stress ulcers, hives and itching, and viral warts, and to prevent aspiration pneumonia during anesthesia.

Route:Oral (Tablets: 200, 300, 400, and 800 mg. Liquid: 300 mg/5 mL) and Parenteral ( Injection: 150 mg/mL).
Dosage: Duodenal ulcers are treated with 800 mg at bedtime, 300 mg 4 times a day at meal times and bedtime, or 400 mg twice a day for 4-6 weeks. Maintenance therapy is 400 mg at bedtime.
Active gastric ulcers are treated with 800 mg at bedtime or 300 mg 4 times a day at meal times and bedtime for up to 8 weeks.
The regimen for GERD is 800 mg twice a day or 400 mg 4 times a day for 12 weeks.
Pathological hypersecretory conditions are treated with 300 mg 4 times daily up to 2400 mg daily.
Heartburn, indigestion and sour stomach may be treated with 200 mg once or twice daily and may be administered up to 30 minutes before ingestion of food or beverages that may cause heart burn.
For hospitalized patients who cannot take oral medications, 300 mg of cimetidine may be administered by intravenous or intramuscular injection every 6-8 hours. A continuous intravenous infusion of 37.5 to 50 mg/hour also may be used.
Pharmacodynamics& Pharmacokinetics check out this link:http://chemistry.clemson.edu/ChemDocs/fa...

Adverse/ Side Effects:
Minor side effects include constipation, diarrhea, fatigue, headache, insomnia, muscle pain, nausea, and vomiting. Major side effects include confusion and hallucinations (usually in elderly or critically ill patients); enlargement of the breasts; impotence (usually seen in patients on high doses for prolonged periods); decreased white blood cell counts. Other side effects include irregular heartbeat, impotence, rash, visual changes, allergic reactions, and hepatitis, excitement and depression.
nervousness.

Nursing Implications:
>>As usual check the correct dose and the 5 rights.
>>Check for any known allergy.
>>Check what other medications the patient is on as cimitidine tend to have various drug interactions like with warfarin, phenytoin, theophylline, lidocaine, amiodarone, metronidazole, loratadine, calcium channel blockers (e.g., diltiazem, felodipine, nifedipine), bupropion, carbamazepine and fluvastatin.
>>Give cimitidine 2 hours after other antacids, digoxin (Lanoxin), ketoconazole (Nizoral), or iron salts ifever.
>>Observe for any side effects.
>>Protect from any harmful risks as patient may have hallucination, confusion, depression or excitement.

Patient鈥檚 education:
>>Inform on the possible side effects.
>>Educate on what signs noted need to be reported promptly.
>>Emphasize on possibility of confusion and hallucination.鈾?/div>

• 1 year ago

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